Thermo Fisher Scientific SLITRK6 Polyclonal Antibody
SLITRK6 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체. Western blot, IHC, ICC/IF에 사용 가능하며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 냉장 또는 냉동 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human Slitrk6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153371 |
Product Specific Information
- A suggested positive control is SK-N-SH cell lysate.
- PA5-20479 can be used with blocking peptide PEP-0599.
Target Information
SLIT and NTRK-like family 6 (Slitrk6) is a member of a protein family (Slitrk1–6) that share two conserved leucine-rich repeat domains in the extracellular region and show homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. Slitrk6 expression has been observed in tongue, lung, gastrointestinal tract, and pancreas. Overexpression of Slitrk6 inhibits neurite outgrowth in cultured neurons, suggesting involvement in neurite outgrowth regulation.
At least two isoforms of Slitrk6 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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