Thermo Fisher Scientific Livin Polyclonal Antibody
Livin 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A로 정제된 1 mg/mL 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Livin (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs contain at least one baculovirus IAP repeat (BIR) motif essential for anti-apoptotic activity.
Livin (also known as ML-IAP) is a novel human IAP family member containing a single BIR domain and a C-terminal RING finger domain.
Two splicing variants (298 and 280 amino acids) both inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but higher in developmental tissues and various cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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