Thermo Fisher Scientific DNAJB4 Polyclonal Antibody
DNAJB4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간, 마우스, 랫트에 반응. 항원 친화 크로마토그래피로 정제, PBS/glycerol 용액 형태로 제공. 연구용으로만 사용 가능.
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- PA549925
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human DNAJB4 (amino acids 112–136). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635378 |
Product Specific Information
This antibody detects endogenous levels of total DNAJB4 protein.
Target Information
DnaJ heat shock induced proteins originate from Escherichia coli and are regulated by the htpR protein. These proteins play a critical role in the HSP70 chaperone system by interacting with HSP70 to stimulate ATP hydrolysis.
They contain cysteine-rich zinc finger regions forming peptide-binding domains responsible for chaperone activity.
DnaJ proteins are key mediators of proteolysis and are involved in protein degradation, exocytosis, and endocytosis.
DNAJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart, and pancreas, with lower expression in brain, placenta, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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