Thermo Fisher Scientific FGF23 Polyclonal Antibody
FGF23 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. Human과 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C에서 보관하며 연구용으로 적합.
- 카탈로그번호
- PA549926
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human FGF23 (aa 151–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635379 |
Product Specific Information
This antibody detects endogenous levels of total FGF23 protein.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in various biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
FGF23 inhibits renal tubular phosphate transport and mutations in this gene are associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. High expression levels have been found in oncogenic hypophosphatemic osteomalacia, a disease caused by abnormal phosphate metabolism. Mutations also cause familial tumoral calcinosis with hyperphosphatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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