Thermo Fisher Scientific PRDX2 Polyclonal Antibody
PRDX2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot에 최적화되어 있으며 인간 시료에서 반응. 합성 펩타이드 면역원 사용, 고순도 정제, 안정적인 액상 형태로 제공.
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Thermo Fisher Scientific PRDX2 Polyclonal Antibody
Applications
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (NVDDSKEYFSKHN) corresponding to the C-terminus amino acids of PRDX2 (aa 186–198) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10978312 |
Product Specific Information
- This antibody is predicted to react with rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Peroxiredoxin (Prx) is a peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins (approximately 50 isoforms) are classified by sequence homology and cysteine-based active sites.
Mammalian Prxs include 6 members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx. Except for Prx VI (1-Cys subgroup), the other five 2-Cys isotypes exhibit thioredoxin-dependent peroxidase (TPx) activity using thioredoxin, thioredoxin reductase, and NADPH as reducing systems.
Mammalian Prxs range from 20–30 kDa and vary in subcellular localization:
- Prx I, II, VI: cytosol
- Prx III: mitochondria
- Prx IV: ER and secretion
- Prx V: peroxisome, mitochondria, and cytosol
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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