Thermo Fisher Scientific Phospho-TrkC (Tyr516) Polyclonal Antibody
Phospho-TrkC (Tyr516) 폴리클로날 항체로, 인간, 생쥐, 랫트에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경계 발달 관련 단백질 NTRK3 검출에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:100–1:300 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human TrkC around the phosphorylation site of Y516 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607715 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in nervous tissue. Isoform B is expressed in relatively large amounts in the adult brain compared to the fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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