Thermo Fisher Scientific Phospho-NF2 (Ser10) Polyclonal Antibody
NF2 단백질의 Ser10 인산화 부위를 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ELISA에 적합. 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human NF2 around the phosphorylation site of S10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608914 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
NF2 encodes a protein, Merlin, that is similar to members of the ERM family of proteins which link cytoskeletal components with membrane proteins. Merlin interacts with cell-surface proteins, cytoskeletal regulators, and ion transport proteins. The gene is highly expressed during embryonic development; in adults, expression is significant in Schwann cells, meningeal cells, lens, and nerve. Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities. Multiple isoforms are produced via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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