Thermo Fisher Scientific TAP1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

ELISA

• Tested Dilution: 1:5,000–1:25,000

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

This product was prepared from monospecific antiserum by delipidation, salt fractionation, and ion-exchange chromatography.
A single precipitin arc was observed against anti-Rabbit Serum when assayed by immunoelectrophoresis.

Target Information

The membrane-associated protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily.
ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein belongs to the MDR/TAP subfamily, which is involved in multidrug resistance.
It participates in pumping degraded cytosolic peptides across the endoplasmic reticulum into the compartment where class I molecules assemble.
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.