Thermo Fisher Scientific Mint1 Polyclonal Antibody
Thermo Fisher Scientific의 Mint1 Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하며, Western blot과 IHC에 적합합니다. Rabbit에서 생산된 비결합형 다클론 항체로, 신경세포막 단백질 상호작용 연구에 유용합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse Mint1 (APBA1) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: MINT1
Target Information
The munc-18 interacting protein (Mint) family comprises adaptor proteins involved in membrane transport and organization. Mammalian Mint isoforms include Mint1, Mint2, and Mint3.
- The C-terminal region is highly conserved, containing PTB and PDZ domains for protein interactions.
- Mint1 and Mint2 are expressed mainly in the brain and bind to Munc18, a component of synaptic vesicle fusion machinery.
- Mint3 is ubiquitously expressed, interacts with APP (amyloid precursor protein), and may regulate APP transport and metabolism.
- Abnormal APP metabolism is linked to early-onset Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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