Thermo Fisher Scientific MUPP1 Polyclonal Antibody
Thermo Fisher Scientific의 MUPP1 Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하며 WB 및 IHC에 적합합니다. Rabbit 유래의 polyclonal 항체로, MUPP1 단백질 특이성을 가지며 연구용으로 사용됩니다. Lyophilized 형태로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse Multiple PDZ domain protein (MPDZ, MUPP1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: MPDZ
Target Information
MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor and co-localizes with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus.
MUPP1 contains 13 PDZ domains but no apparent catalytic domain. It is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM).
MUPP1 may function as a multivalent scaffold protein that recruits various proteins to tight junctions and interacts with claudin-8, playing a role in tight junction barrier function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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