Thermo Fisher Scientific GTF2IRD1 Monoclonal Antibody (OTI9A3), TrueMAB
인간 GTF2IRD1 단백질(aa 400-540)에 특이적인 mouse monoclonal antibody. Western blot에 최적화된 TrueMAB 형식. 1 mg/mL 액상, PBS/BSA/glycerol buffer에 보관. 연구용 전용 제품으로 Williams-Beuren syndrome 관련 연구에 적합.
- 카탈로그번호
- TA809948
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 400–540 of human GTF2IRD1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Williams-Beuren syndrome (WBS) is a developmental disorder caused by a hemizygous microdeletion on chromosome 7q11.23. It is characterized by physical, cognitive, and behavioral traits such as facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies, and neurologic abnormalities.
The WBSCR11 gene, also known as GRF2IRD1, GTF3, Cream1, and MusTRD1 in humans and BEN in mice, is located within the WBS deletion region and may contribute to developmental symptoms due to the loss of its encoded transcription factor. WBSCR11 is expressed in all adult tissues as several variants and shows discrete spatial and temporal expression during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: TA809948_GTF2IRD1_Q9UHL9-1_House_mouse.svg / TA809948_GTF2IRD1_Q9UHL9-1_House_mouse_PDP.jpeg)
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