Thermo Fisher Scientific CCKBR Polyclonal Antibody
Rabbit polyclonal antibody targeting human CCKBR. Validated for Western blot and IHC (paraffin). Supplied as liquid, 1 mg/mL concentration. Recommended positive control: unboiled HeLa extract. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 271–363 of Human CCK-BR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544645 |
Product Specific Information
- Recommended positive control: Unboiled HeLa cell extract
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CCKBR is a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has high affinity for both sulfated and nonsulfated CCK analogs and is found mainly in the central nervous system and gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR expression has been reported in brain, colon, pancreas, stomach, thyroid, and various cancers.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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