Thermo Fisher Scientific alpha-2c Adrenergic Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human alpha-2c adrenergic receptor for WB and IHC applications. Recognizes amino acids 318–409 region. Suitable for HeLa and HepG2 controls. Unconjugated, liquid form, 0.62 mg/mL concentration. Store at 4°C short te...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 318–409 of Human alpha-2c Adrenergic Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544642 |
Product Specific Information
- Recommended positive controls: HeLa, HepG2
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Alpha-2-adrenergic receptors belong to the G protein-coupled receptor superfamily and include three subtypes: alpha2A, alpha2B, and alpha2C. These receptors regulate neurotransmitter release from sympathetic nerves and adrenergic neurons in the central nervous system.
Studies in mice indicate that both alpha2A and alpha2C subtypes are required for normal presynaptic control of transmitter release. The alpha2A subtype inhibits release at high stimulation frequencies, while alpha2C modulates neurotransmission at lower activity levels.
This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated regions.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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