Thermo Fisher Scientific CXCR5 Polyclonal Antibody
CXCR5 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Western blot과 Immunocytochemistry에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며 장기 보관 시 -20°C에서 냉동 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 194–286 of Human CXCR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544646 |
Product Specific Information
- Recommended positive control: HepG2
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CXCR5 (C-X-Chemokine Receptor Type 5, CD185), also known as Burkitt lymphoma receptor 1 (BLR1), belongs to the CXC chemokine receptor family.
It is a G protein-coupled seven transmembrane receptor for chemokine BLC and is specifically expressed in Burkitt’s lymphoma and lymphatic tissues such as lymph node follicles and spleen.
CXCR5 plays an essential role in B cell migration and has been reported in various human tissues including blood and salivary gland, as well as in animal lymphatic organs, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a seven membrane-spanning helix structure. They exist in both active and inactive forms and participate in signaling via G-proteins and downstream effectors.
Research on GPCRs continues to drive pharmacological studies for new drug candidates, with well-known GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(PA5-27170_CXCR5_P32302-1_Rabbit.svg 및 PA5-27170_CXCR5_P32302-1_Rabbit_PDP.jpeg 이미지 포함)
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