Thermo Fisher Scientific FANCD2 Monoclonal Antibody (FI-17)
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA116570 | - | Thermo Fisher Scientific MA116570 FANCD2 Monoclonal Antibody (FI-17) 100 ul pk | 재고문의 | pk | 595,000원 | - | 654,500원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:2,000
View 2 publications 2 publications
Immunocytochemistry (ICC/IF)
1:10-1:500
View 1 publication 1 publication
Immunoprecipitation (IP)
Assay-Dependent
ChIP assay (ChIP)
1:10-1:500
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
FI-17
Immunogen
FANCD2 fusion protein
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.1% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_568533
Product Specific Information
By Western blot, this antibody recognizes a band at ~155 and ~162 kDa (post-translationally modified form).
Suggested positive control: Hela whole cell extract.
Target Information
FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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