Thermo Fisher Scientific Periostin Polyclonal Antibody
Thermo Fisher Scientific의 Periostin Polyclonal Antibody는 마우스와 랫트 시료에서 사용 가능하며, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합 항체로, E. coli 유래 recombinant Periostin을 면역원으로 사용합니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived rat Periostin recombinant protein (Position: K577–Q810) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746965 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as an osteoblast-specific factor. It is a secreted protein that binds heparin and functions as a ligand for α(V)β(3) and α(V)β(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule, playing roles in osteoblast recruitment, spreading, and attachment. Periostin is mainly detected in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1 (TGFβ1). It contains a signal sequence, a cysteine-rich domain, a fourfold repeated domain homologous to insect fasciclin, and a C-terminal domain.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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