Thermo Fisher Scientific PON1 Polyclonal Antibody
Thermo Fisher Scientific의 PON1 Polyclonal Antibody는 마우스 PON1 단백질을 인식하는 토끼 유래 IgG 항체입니다. ELISA에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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Applications
- ELISA (ELISA): Tested dilution 2–8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse PON1 recombinant protein (Position: A30–D274) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746961 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The paraoxonase (PON) gene-family in humans has three members: PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3–22.1.
PON1 is synthesized primarily in the liver and secreted into the plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes the active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and is considered an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-79846_PON1_P52430-1_Rabbit_PDP.jpeg)
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