Thermo Fisher Scientific CD307e (FcRL5) Monoclonal Antibody (307307)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

307307

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL5/FCRL3 Gln16-Arg844 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FcRL5,uniProtId:Q96RD9-1,ncbiNodeId:9606,antigenRange:16-844,antigenLength:977,antigenImageFileName:MA5-24020_FcRL5_Q96RD9-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24020_FcRL5_Q96RD9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2605923

Product Specific Information

In direct ELISAs, 100% cross-reactivity with recombinant human (rh) FCRL3 is observed and no cross-reactivity with rhFCRL1, 2, or 4 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 function as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role for the pathogenesis of B-cell lymphoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.