
Thermo Fisher Scientific GPNMB Monoclonal Antibody (303822)
Thermo Fisher Scientific의 GPNMB 단클론 항체(303822)는 인간 GPNMB 단백질을 특이적으로 인식하는 Mouse IgG2b 항체입니다. Western blot, ICC/IF, Flow cytometry에 적합하며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL | - |
| Flow Cytometry (Flow) | 0.25 µg per million cells | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 303822 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Osteoactivin/GPNMB isoform 2 (Ala22–Asn486) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607806 |
Product Specific Information
- In direct ELISAs, no cross-reactivity with recombinant mouse Osteoactivin is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein homologous to the pMEL17 precursor, a melanocyte-specific protein.
GPNMB is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines.
It may be involved in growth delay and reduction of metastatic potential.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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