Thermo Fisher Scientific PSCA Polyclonal Antibody
PSCA 단백질(aa 41-90)에 특이적인 Rabbit Polyclonal Antibody. Western blot에 1:500~1:1,000 희석 사용. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제, PBS/glycerol 저장. 전립선암 및 종양 연구용.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 41–90 of Human PSCA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2718906 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is >95% as determined by SDS-PAGE.
Target Information
PSCA (Prostate Stem Cell Antigen) is a cell surface antigen overexpressed in approximately 40% of primary prostate cancers and up to 100% of metastatic cases. It is also overexpressed in many transitional cell and pancreatic carcinomas. Antibodies against PSCA have been shown to inhibit tumorigenesis, slow tumor growth, prolong survival, and prevent metastasis in preclinical xenograft models, suggesting PSCA may serve as a prognostic marker or therapeutic target in prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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