Thermo Fisher Scientific Myc Tag Polyclonal Antibody
Myc 태그 단백질 검출용 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 – 1:30,000 |
| Immunocytochemistry (ICC/IF) | 1:100 – 1:400 |
| ELISA | 1:1,000 – 1:30,000 |
| Immunoprecipitation (IP) | 1 – 4 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Tag |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide representing amino acid residues 410–419 (EQKLISEEDL) of Human myc conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Rabbits were immunized with a synthetic peptide representing amino acid residues 410–419 (EQKLISEEDL) of human myc conjugated to KLH. The antibody was isolated by affinity chromatography using the peptide immobilized on solid support.
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein involved in cell cycle progression, apoptosis, and cellular transformation. The encoded protein forms a heterodimer with the transcription factor MAX, binding to the E-box DNA consensus sequence to regulate target gene transcription. Gene amplification is frequently observed in various human cancers, and translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma. Translation can initiate from both an upstream non-AUG (CUG) and a downstream AUG start site, producing two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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