Thermo Fisher Scientific Myc Tag Polyclonal Antibody
Myc 태그 인식용 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. 닭 IgY 기반으로 높은 특이성과 재현성을 제공하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 – 1:30,000 |
| Immunocytochemistry (ICC/IF) | 1:100 – 1:400 |
| ELISA | 1:1,000 – 1:30,000 |
| Immunoprecipitation (IP) | 1 – 4 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Tag |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide representing amino acid residues 410–419 (EQKLISEEDL) of human myc conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Chickens were immunized with a synthetic peptide representing amino acid residues 410–419 (EQKLISEEDL) of human myc conjugated to KLH. The antibody was isolated by affinity chromatography using the peptide immobilized on solid support.
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein involved in cell cycle progression, apoptosis, and cellular transformation. It forms a heterodimer with MAX, binding to the E-box DNA consensus sequence to regulate transcription of specific genes. Myc gene amplification is frequently observed in various human cancers, and translocations are associated with Burkitt lymphoma and multiple myeloma. Translation may initiate from both upstream non-AUG (CUG) and downstream AUG start sites, yielding two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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