Thermo Fisher Scientific CD81 Chimeric Recombinant Rabbit Monoclonal Antibody (1.3.3.22)
CD81 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. Protein A로 정제된 액상 제품으로 4°C 단기 보관, -20°C 장기 보관 권장. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1.3.3.22 |
| Immunogen | This antibody was raised by immunizing mice with a B-Cell line derived from a Burkitt lymphoma. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074723 |
Product Specific Information
Specificity: 1.3.3.22 antibody recognizes CD81.
Human CD81 is a member of the tetraspanin family of leukocyte cell surface molecules involved in signal transduction, cell-cell adhesion, and cellular activation.
CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus and is present on a wide variety of leukocytes.
Target Information
CD81 (TAPA-1) is a member of the tetraspanin family, expressed on most nucleated cells, especially germinal center B cells.
It forms complexes with tetraspanin proteins, integrins, coreceptors, and MHC molecules, influencing adhesion, morphology, activation, proliferation, and differentiation of immune cells.
In muscle cells, CD81 promotes cell fusion and myotube maintenance.
It functions as a receptor for the hepatitis C virus E2 envelope protein.
Antibodies to CD81 exhibit anti-proliferative effects on lymphoid cell lines and are associated with tumor-suppressor gene regions, making CD81 a candidate gene for malignancies.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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