Thermo Fisher Scientific CD81 Chimeric Recombinant Rabbit Monoclonal Antibody (1.3.3.22)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Specificity: 1.3.3.22 antibody recognizes CD81.
Human CD81 is a member of the tetraspanin family of leukocyte cell surface molecules involved in signal transduction, cell-cell adhesion, and cellular activation.
CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus and is present on a wide variety of leukocytes.

Target Information

CD81 (TAPA-1) is a member of the tetraspanin family, expressed on most nucleated cells, especially germinal center B cells.
It forms complexes with tetraspanin proteins, integrins, coreceptors, and MHC molecules, influencing adhesion, morphology, activation, proliferation, and differentiation of immune cells.
In muscle cells, CD81 promotes cell fusion and myotube maintenance.
It functions as a receptor for the hepatitis C virus E2 envelope protein.
Antibodies to CD81 exhibit anti-proliferative effects on lymphoid cell lines and are associated with tumor-suppressor gene regions, making CD81 a candidate gene for malignancies.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.