Thermo Fisher Scientific Phospho-MCM2 (Ser53) Polyclonal Antibody
Phospho-MCM2 (Ser53) 폴리클로날 항체로 인간 및 마우스 시료에 반응. IHC 및 IHC(파라핀) 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. DNA 복제 조절 단백질 MCM2의 인산화 부위를 표적.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide representing a portion of Human Minichromosomal Maintenance Deficient 2 surrounding Serine 53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Zebrafish, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, and Gorilla
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication.
MCM2 (also called CDCL1, mitotin, and BM28) is a human nuclear protein crucial in the cell cycle, involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins.
MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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