Thermo Fisher Scientific Phospho-Aurora A (Thr288) Polyclonal Antibody
Aurora A kinase의 Thr288 인산화 부위를 인식하는 rabbit polyclonal antibody. 인간 시료에 반응하며 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약으로 4°C에서 보관. 암 연구 및 세포주기 조절 연구에 활용.
- 카탈로그번호
- IHC00067x (2개 옵션)
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-Aurora A (Thr288) Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 1:100–1:500
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region surrounding residue 288 when Threonine 288 is phosphorylated of human Aurora A Kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes.
Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, related to the centrosome/spindle pole region during chromosome segregation.
Aurora A is highly expressed in testis and weakly in skeletal muscle, thymus, and spleen.
It is considered a potential target for anticancer drug development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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