Thermo Fisher Scientific CENP-F/Mitosin Polyclonal Antibody
CENP-F 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 세포에서의 면역세포화학(ICC/IF)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.25 mg/mL 농도의 액상 형태입니다. 4°C 보관, 습식 얼음 배송 조건입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1800 and 1850 of human Centromere Protein F |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla, Chimpanzee, and Northern white-cheeked gibbon.
Target Information
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2, it associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization suggests a role in chromosome segregation during mitosis. It may form a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft-versus-host disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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