Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (OTI3H5), TrueMAB

Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (OTI3H5), TrueMAB

Applications and Tested Dilutions

• Western Blot (WB): 1:400–1:4,000
• Immunocytochemistry (ICC/IF): 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The RAPGEF1 gene encodes a human guanine nucleotide exchange factor that transduces signals from CRK by binding to the SH3 domain of CRK and activating several members of the Ras family of GTPases.
This signaling cascade may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.