Thermo Fisher Scientific IL6R Monoclonal Antibody (OTI2F4), TrueMAB
인간 IL6R(CD126)에 특이적인 단클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. TrueMAB 포맷으로 높은 특이성과 재현성 제공. 동결건조 형태로 안정적이며, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F4 |
| Immunogen | Full length human recombinant protein of human IL6R produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Interleukin 6 receptor (IL6R), also known as CD126, is a type I cytokine receptor and a subunit of the IL6 receptor complex.
IL6 is a potent pleiotropic cytokine regulating cell growth, differentiation, and immune response.
The IL6 receptor complex includes IL6ST/GP130, shared by multiple cytokines.
Dysregulated IL6 and IL6R expression is associated with diseases such as multiple myeloma, autoimmune disorders, and prostate cancer.
Alternative splicing produces distinct isoforms, and a pseudogene is located on chromosome 9.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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