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Thermo Fisher Scientific Phospho-c-Raf (Ser471) Polyclonal Antibody
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Phospho-c-Raf (Ser471) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. WB, IHC, ICC, ELISA 등 다양한 응용 가능. KLH 결합 합성 인산화 펩타이드 면역원 사용. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용 적합.
- 카탈로그번호
- BS-5649R
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 02. 오전 02:35
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Thermo Fisher Scientific BS-5649R Phospho-c-Raf (Ser471) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
569,000원VAT 포함 625,900원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-c-Raf (Ser471) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser471 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) functioning downstream of the Ras family of membrane-associated GTPases. Once activated, Raf-1 phosphorylates and activates MEK1 and MEK2, which in turn activate ERK1 and ERK2. Activated ERKs regulate gene expression involved in cell division, apoptosis, differentiation, and migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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