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Thermo Fisher Scientific Phospho-c-Raf (Thr269) Polyclonal Antibody
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인간, 마우스, 랫트 반응성의 Rabbit Polyclonal 항체로 c-Raf Thr269 인산화 부위를 인식합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Protein A 정제 및 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- pk
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569,000원VAT 포함 625,900원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-c-Raf (Thr269) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Thr269 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) functioning downstream of Ras GTPases. Upon activation, Raf-1 phosphorylates and activates MEK1/2, which subsequently activate ERK1/2. Activated ERKs regulate gene expression related to cell division, apoptosis, differentiation, and migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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