Thermo Fisher Scientific BNP Monoclonal Antibody (50E1)
인체 BNP를 인식하는 단클론 항체로 Western blot 및 ELISA에 사용 가능. 단백질 A로 정제된 액상 형태이며 4°C 보관. 심부전 관련 연구 및 BNP 단백질 발현 분석에 적합.
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Applications
- Western Blot (WB): Assay-dependent
- ELISA: Assay-dependent
- 관련 논문: 1편
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 50E1 |
| Immunogen | Synthetic peptide corresponding to Human BNP (whole molecule) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1954930 |
Product Specific Information
MA1-34237 detects BNP from human samples.
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. It undergoes two cleavage events—one intracellularly and another after secretion into the blood. The protein’s biological actions include:
- Natriuresis
- Diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Regulation of cardiovascular homeostasis
High levels of this protein in the bloodstream are indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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