Thermo Fisher Scientific CD85j (ILT2) Polyclonal Antibody
Thermo Fisher Scientific CD85j (ILT2) Polyclonal Antibody는 인간 CD85j/ILT2 단백질을 인식하는 염소 유래 IgG 항체로, WB, Flow Cytometry 및 Neutralization 분석에 사용됩니다. 고순도의 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관 가능합니다.
- 카탈로그번호
- PA547240
- 판매단위
- pk
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Thermo Fisher Scientific CD85j (ILT2) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| Neutralization (Neu) | 0.3–1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human LILRB1/CD85j/ILT2 Gly24–His458 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606520 |
Product Specific Information
- In direct ELISAs, approximately 25% cross-reactivity with recombinant human ILT4 and 15% cross-reactivity with recombinant human ILT5 are observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of antibody by the LAL method.
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family located at chromosomal region 19q13.4.
The encoded protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
It is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits stimulation of an immune response.
This mechanism helps control inflammatory responses and cytotoxicity, focusing the immune response and limiting autoreactivity.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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