
Thermo Fisher Scientific XDH Monoclonal Antibody (OTI5D8), TrueMAB
XDH 단백질을 인식하는 마우스 모노클로날 항체로 Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, 무보존제 PBS 완충액에 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–280 of human XDH produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
XDH (Xanthine Dehydrogenase) is a molybdenum-containing hydroxylase involved in purine oxidative metabolism. The enzyme functions as a homodimer and can convert to xanthine oxidase through reversible sulfhydryl oxidation or irreversible proteolytic modification.
Defects in XDH cause xanthinuria, may contribute to adult respiratory distress syndrome, and can potentiate influenza infection through oxygen metabolite-dependent mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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