Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI2D2), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The vertebrate ocular lens is composed primarily of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (encoded by BFSP1), are expressed after fiber cell differentiation. These proteins form the beaded filament (BF), a unique cytoskeletal structure.
Mutations in BFSP1 are associated with autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.