Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI1F4), TrueMAB
Human BFSP1 단백질(aa 405-665)에 특이적인 Mouse IgG1 단클론 항체. Western blot 및 IHC에 사용 가능. Lyophilized 형태로 제공되며 PBS buffer(8% trehalose) 포함. 연구용으로만 사용.
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Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI1F4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of human BFSP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
More than 99% of the vertebrate ocular lens is composed of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (BFSP1), are expressed only after fiber cell differentiation begins. These proteins form a unique cytoskeletal structure called the beaded filament (BF).
Mutations in the BFSP1 gene cause autosomal recessive cortical juvenile-onset cataract.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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