Thermo Fisher Scientific IL12B Monoclonal Antibody (OTI3H6), TrueMAB
IL12B 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료 반응성, carrier-free 형태로 제공되어 다양한 결합 실험에 적합. 고순도 친화 크로마토그래피 정제, 안정적인 동결건조 제형.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Full length human recombinant protein of human IL12B produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product for desalting: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine acting on T and NK cells with diverse biological activities.
Interleukin 12 is a disulfide-linked heterodimer composed of a 40 kDa subunit encoded by IL12B and a 35 kDa subunit encoded by IL12A.
It is expressed by activated macrophages and plays a key role in Th1 cell development and maintenance of memory/effector Th1 cells.
Overexpression has been observed in multiple sclerosis (MS) patients, suggesting involvement in disease pathogenesis.
Promoter polymorphisms are linked to asthma severity in children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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