Thermo Fisher Scientific HSF2 Monoclonal Antibody (OTI4B2), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing heat shock genes. In eukaryotes, transcription of these genes is regulated mainly by heat shock transcription factors (HSF1 and HSF2).
HSF1 and HSF2 are upregulated by estrogen at both mRNA and protein levels. HSF1 exists as a monomer under normal conditions and becomes active upon trimerization and nuclear translocation.
HSF2 is associated with differentiation and development and, like HSF1, binds DNA as a trimer. Both are induced by proteasome inhibitors of the ubiquitin pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.