Thermo Fisher Scientific Ku70 Monoclonal Antibody (D1-A6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1000-1:2000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

D1-A6

Immunogen

Recombinant protein within human ku70 aa 1-150 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ku70,uniProtId:P12956-1,ncbiNodeId:9606,antigenRange:1-150,antigenLength:609,antigenImageFileName:MA5-42413_Ku70_P12956-1_House_mouse.svg,antigenImageFileNamePDP:MA5-42413_Ku70_P12956-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 40% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911554

Product Specific Information

Positive Control: Hela, HepG2, A431, D3, 293T, A549, COS-1, human kidney tissue, human liver tissue, human brain, human thymus tissue, human placentae tissue, mouse kidney tissue, mouse liver tissue, mouse thymus tissue, mouse testis tissue, human tonsil tissue,human breast cancer tissue.

Subcellular Location: Nucleus

Target Information

XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.