Thermo Fisher Scientific Nectin 3 Polyclonal Antibody
Thermo Fisher Scientific의 Nectin 3 Polyclonal Antibody는 인간 PVRL3/Nectin-3/CD113 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 ELISA에 적합하며, 보존제가 없는 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PVRL3 protein (Met1–Asp400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788119 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PVRL3/Nectin-3/CD113.
Target Information
Nectin-3 is an 83 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily involved in cell-cell adhesion. Nectins (1–4) interact homophilically and heterophilically to form various junctions, including adherens junctions, synaptic junctions, and Sertoli cell–spermatid junctions.
Nectin-3 (also known as PRR3) is predominantly expressed in testis and placental tissues and interacts with afadin at cadherin-based junctions. Its ectodomain also binds strongly to CD155 (Poliovirus Receptor).
Injection of antibody 103-A1 into seminiferous tubules disrupts actin filaments in Sertoli cells and causes exfoliation of maturing spermatids from the seminiferous epithelium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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