Thermo Fisher Scientific Neurogenin 2 Polyclonal Antibody
Rabbit polyclonal antibody against Human Neurogenin 2 (NEUROG2). Validated for WB, ICC/IF, and IP applications. Preservative-free formulation with high specificity. Suitable for neurogenesis and neuronal differentiation research.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 4–8 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of Human NEUROG2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788120 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody shows specificity for Human NEUROG2.
Target Information
Neurogenin-2 (NEUROG2) is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factors that play a key role in neurogenesis from migratory neural crest cells. During mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia, while Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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