
Thermo Fisher Scientific Nectin 1 Polyclonal Antibody
Human PVRL1/Nectin 1을 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합. 보존제가 없는 액상 형태로 제공되며, 장기 보관 시 -20°C에서 냉동 보관 권장. 단백질 A로 정제된 고순도 항체.
- 카탈로그번호
- PA580849
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PVRL1 protein (Met1–Thr334) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788118 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PVRL1/HVEC/CD111.
Target Information
This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells.
It is a calcium-independent cell-cell adhesion molecule of the immunoglobulin superfamily, containing three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region.
Nectin 1 acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-80849_Nectin_1_Q15223-1_Rabbit.svg, PA5-80849_Nectin_1_Q15223-1_Rabbit_PDP.jpeg)
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