Thermo Fisher Scientific Nectin 1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PVRL1/HVEC/CD111.

Target Information

This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells.
It is a calcium-independent cell-cell adhesion molecule of the immunoglobulin superfamily, containing three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region.
Nectin 1 acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-80849_Nectin_1_Q15223-1_Rabbit.svg, PA5-80849_Nectin_1_Q15223-1_Rabbit_PDP.jpeg)