Thermo Fisher Scientific N4BP2L2 Monoclonal Antibody (OTI7F5), TrueMAB
인간 N4BP2L2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화되어 있습니다. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F5 |
| Immunogen | Full length human recombinant protein of human N4BP2L2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N4BP2L2 (NEDD4-binding protein 2-like 2), also known as PFAAP5 (phosphonoformate immuno-associated protein 5), is a 583 amino acid nuclear protein potentially involved in transcriptional regulation. It is phosphorylated on Ser 199 in response to DNA damage, likely by ATM or ATR. Primarily expressed in bone marrow, N4BP2L2 is down-regulated after exposure to arsenic compounds, preceding neutropenia. PFAAP5 interacts with Gfi-1 and Neutrophil Elastase, proteins implicated in neutropenia disorders. Defects in the ELA2 gene encoding Neutrophil Elastase cause cyclic haematopoiesis, leading to reduced neutrophil counts and increased susceptibility to infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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