Thermo Fisher Scientific PI3K p85/p55 Recombinant Rabbit Monoclonal Antibody (10L6B7)
PI3K p85/p55 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, ICC/IF, ELISA에 적합하며 높은 특이성과 재현성을 제공. 마우스 및 랫트 반응성. 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,500–1:18,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10L6B7 |
| Immunogen | A synthetic peptide of human PI3 Kinase p85 alpha/beta (NP_852664.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094402 |
Product Specific Information
Immunogen sequence: RLYEE
Target Information
Phosphoinositide 3-kinase (PI3K, phospho PI3K) binds to activated (phosphorylated) protein-Tyr kinases via its SH2 domain and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phospho PI3K is essential for insulin-stimulated glucose uptake and glycogen synthesis in insulin-sensitive tissues. During insulin stimulation, it also binds to IRS-1. Growth factors and hormones trigger this phosphorylation event, coordinating cell growth, cell cycle entry, cell migration, and cell survival.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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