Thermo Fisher Scientific STING Recombinant Rabbit Monoclonal Antibody (9V9A3)
STING 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, HEK293 세포에서 발현된 IgG 형식의 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:800 |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 400 µg–600 µg extracts |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9V9A3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 150–379 of human STING/TMEM173 (NP_938023.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.29 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094269 |
Product Specific Information
Immunogen sequence:
KGNFNVAHGL AWSYYIGYLR LILPELQARI RTYNQHYNNL LRGAVSQRLY ILLPLDCGVP DNLSMADPNI RFLDKLPQQT GDHAGIKDRV YSNSIYELLE NGQRAGTCVL EYATPLQTLF AMSQYSQAGF SREDRLEQAK LFCRTLEDIL ADAPESQNNC RLIAYQEPAD DSSFSLSQEV LRHLRQEEKE EVTVGSLKTS AVPSTSTMSQ EPELLISGME KPLPLRTDFS
Target Information
STING is a 379-amino-acid signaling protein that plays a key role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferon (IFN-α and IFN-β) expression, contributing to antiviral responses. STING is also involved in apoptotic signaling through association with MHC-II and may influence type I interferon induction. It is typically localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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