Thermo Fisher Scientific Phospho-EphB1 (Tyr928) Polyclonal Antibody
Phospho-EphB1 (Tyr928) 폴리클로날 항체로, 인간 EPHB1의 Tyr928 인산화 부위를 인식합니다. Western blot에 최적화되어 있으며, 1:1,000–1:3,000 희석으로 사용 가능합니다. 신경계 발달 및 혈관 형성 연구에 활용됩니다.
- 카탈로그번호
- PA5118756
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB1 around the phosphorylation site of Tyr928 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903256 |
Target Information
EPHB1 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play key roles in biological processes such as nervous system development, angiogenesis, and synapse formation and maturation.
EphB1 and other EphB family members are type I membrane-spanning proteins composed of immunoglobulin, fibronectin type III, and cysteine-rich subdomains in the ectodomain, and a cytoplasmic tyrosine kinase domain upstream of a carboxy-terminal sterile alpha motif (SAM) domain.
EphB family proteins bind to ephrin-B class ligands, which are also transmembrane proteins capable of bidirectional signaling. EphB1 is primarily expressed in developing neural structures and vascular endothelium. Upon binding ephrin-B1, EphB1 regulates cell attachment and assembly.
Members of this family are implicated in neuronal and vascular cell targeting.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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