Thermo Fisher Scientific PLIN3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PLIN3 (TIP47) for WB and IP applications. Recognizes residues 125–175 of human Perilipin-3. Supplied as liquid, 1 mg/mL, stored at 4°C. Predicted to cross-react with orangutan. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 to 175 of Human Perilipin-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
TIP47 (Perilipin-3) is a cargo protein involved in trafficking of the mannose-6-phosphate receptor between endosomes and the Golgi complex. Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolases from the Golgi to endosomes and then return to the Golgi complex. The protein interacts with cytoplasmic domains of both cation-independent and cation-dependent MPRs and is required for endosome-to-Golgi transport. It also binds directly to the GTPase RAB9, increasing its affinity for cargo. TIP47 has been localized in milk fat globule membranes of human and bovine origin and described as a placental protein. Elevated levels have been observed in circulation of cervix carcinoma patients, suggesting potential as an oncodevelopmental marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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