Thermo Fisher Scientific Rituximab Chimeric Recombinant Rabbit Monoclonal Antibody (10F381 (rituximab))
Thermo Fisher Scientific의 Rituximab Chimeric Recombinant Rabbit Monoclonal Antibody (10F381)는 CD20 항원을 인식하는 고특이성 항체로, 인간 및 영장류 시료에 적합합니다. HEK293 세포에서 발현된 재조합 단클론 항체이며, Flow Cytometry에 최적화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10F381 (rituximab) |
| Immunogen | Human lymphoblastoid cell line SB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074223 |
Product Specific Information
Specificity: CD20 (Human B-lymphocyte-restricted differentiation antigen, Bp35) — a hydrophobic transmembrane protein (~35 kDa) located on pre-B and mature B lymphocytes, and most B-cell non-Hodgkin’s lymphomas. It is not found on stem cells, pro-B cells, normal plasma cells, or other normal tissues.
Target Information
Rituximab (Rituxan) is a humanized monoclonal antibody approved by the U.S. FDA for treatment of autoimmune diseases and cancers such as non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, idiopathic thrombocytopenic purpura, and pemphigus vulgaris. Rituximab targets the CD20 protein on B cells, inducing cell death upon binding.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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