Thermo Fisher Scientific Phospho-MEF2D (Ser180) Polyclonal Antibody
Phospho-MEF2D (Ser180) 폴리클로날 항체로, 인간·생쥐·랫드 시료에서 MEF2D 인산화 상태를 검출 가능. WB, IHC, ICC, ELISA에 적용 가능하며, Protein A로 정제된 액상 항체. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family regulate muscle and neuronal cell differentiation and development, influenced by class II histone deacetylases. Fusions with DAZAP1 have been found in acute lymphoblastic leukemia cell lines, suggesting a role in leukemogenesis. The encoded protein may also be associated with Parkinson’s disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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