Thermo Fisher Scientific IL9R alpha Monoclonal Antibody (AH9R7)

Applications

Flow Cytometry (Flow)

• Assay-dependent

ELISA (ELISA)

• Assay-dependent

Functional Assay (Functional)

• Assay-dependent

Product Specifications

Additional Formats

• PE
• Request custom conjugation

Product Specific Information

This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells, and neurons.
Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection.
Functional Application: Blocking.

Target Information

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. Ligand binding leads to activation of JAK kinases and STAT proteins, triggering diverse biological responses.
This gene is located at the pseudoautosomal regions of X and Y chromosomes and has been associated with asthma development. Multiple pseudogenes exist on chromosomes 9, 10, 16, and 18. Alternatively spliced transcript variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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