Thermo Fisher Scientific TRPM5 Polyclonal Antibody
TRPM5 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 사용 가능. 합성 펩타이드를 면역원으로 제작되었으며, 비결합형 상태로 동결건조되어 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
- 카탈로그번호
- OST00075W
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from zebrafish TRPM5, conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1961176 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
Target Information
This gene encodes a member of the transient receptor potential protein family, a diverse group of proteins with structural features typical of ion channels.
TRPM5 plays an important role in taste transduction and functions as a calcium-activated, non-selective cation channel that conducts Na⁺, K⁺, and Cs⁺ ions but not Ca²⁺ ions.
It is activated by lower concentrations of intracellular Ca²⁺ and inhibited by higher concentrations.
Additionally, it is a temperature-sensitive, heat-activated channel showing a steep increase of inward currents between 15°C and 35°C.
The gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5 and is imprinted, expressed exclusively from the paternal allele.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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